Tuipulotu, a 2023 second-round pick, showed 8.5 sacks last season and could inherit more snaps if Mack is out. A breakout in 2025 would solidify his role and offer real fantasy upside in the event of extended absence.

Tuipulotu steps into a lead edge role replacing Bosa, with Mack providing veteran pressure and a path to consistent impact.

Tuipulotu is identified as a breakout edge presence with the potential to approach double-digit sacks, benefiting from the Chargers' pass-rush scheme and improved health. His role could significantly impact the defense’s overall pressure and fantasy upside.

Tuipulotu brings depth to LA’s front as a versatile defender who can pressure up the middle and edges. Week 1 test against KC’s reconfigured interior could hinge on his ability to collapse pockets and disrupt Mahomes’ rhythm alongside Mack.

Tuipulotu represents another Chargers edge threat KC must handle in Week 1, adding depth behind Mack and testing KC’s left tackle and guard duo as they adjust to high-end rush schemes.